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- A personality disorder indicated by a pattern of lying, exploitation, heedlessness, arrogance, sexual promiscuity, low self-control, and lack of empathy and remorse. Violent and criminal offenses may be indicative of this disorder.
- (obsolete) A mental illness; insanity.
- 1861, Sutherland, Alex John, “Croonian Lectures. On the Pathology, Morbid Anatomy, and Treatment of Insanity”, in The Journal of Mental Science, volume 7, number 36, Association of Medical Officers of Asylums and Hospitals for the Insane, retrieved 2021-03-01:
- It is true that insanity may originate in the mind, as well as in the body, but diseased action must take place in the brain, otherwise we have not, as has been well observed, “a true psychopathy.”