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OTP (plural OTPs)
- (cryptography) Initialism of .
- (computing) Initialism of : a password that is valid for only one login session or transaction.
- (fandom slang) Initialism of : the romantic pairing preferred by an author or reader of fan fiction.
- (electronics) one-time programmable, for electronic devices that can only be programmed once.
- (instant messaging) On the phone.