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From Ancient Greek καχεξία (kakhexía), from κακός (kakós, bad, wretched) + ἔχω (ékhō, to have).


IPA(key): /kəˈkɛksɪə/


cachexia (countable and uncountable, plural cachexias)

  1. (medicine, pathology) A systemic wasting of muscle tissue, with or without loss of fat mass, that accompanies a chronic disease.
    • 2007, Lawrence E. Harrison, 84: Nutritional Support for the Cancer Patient, Alfred E. Chang, Patricia A. Ganz, Daniel F. Hayes, Timothy Kinsella, Harvey I. Pass, Joan H. Schiller, Richard M. Stone, Victor Strecher (editors), Oncology: An Evidence-Based Approach, page 1488,
      Cancer cachexia is a complex syndrome clinically manifest by progressive involuntary weight loss and diminished food intake and characterized by a variety of biochemical alterations.
    • 2007, Toby C. Campbell, Jamie H. Von Roenn, Chapter 11: Anorexia/Weight Loss, Ann M. Berger, John L. Shuster, Jamie H. Von Roenn (editors), Principles and Practice of Palliative Care and Supportive Oncology, page 125,
      Cancer cachexia is a complex metabolic process, due to both host and tumor factors, which results in excess catabolism as well as aberrant fat and carbohydrate metabolism.
    • 2008, Mary Marian, Scott A. Shikora, Mary Russell, Clinical Nutrition for Surgical Patients, page 84,
      Preoperative nutritional therapy in CHF[Cardiac Heart Failure] patients with cachexia is associated with improved postoperative survival rates (56).
    • 2009, Connie W. Bales, Christine S. Ritchie, Handbook of Clinical Nutrition and Aging, page 158,
      While sarcopenia occurs very commonly with aging, cachexia occurs mainly in association with acute or chronic disease.

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